Note: This post may contain statements that I no longer consider true.
See: The Vivos mRNA Appliance Didn't Improve My Obstructive Sleep Apnea.

I’ve been using my Vivos mRNA Appliance for eleven months now, so in theory I’m nearly half-way through my treatment… although I did notice treatments as long as 35 months in Vivos’s most recent real-world data submission to the FDA, so perhaps I’m only a third of the way there. Nevertheless, it’s all good news this month: my AHI continues to drop, as does my CPAP pressure trend, I’m exercising more, and my health continues to improve.

The biggest change this month has been that I’ve started doing some deliberate cardio exercise again, taking my skipping rope down to the beach each day weather permits and doing some skips. I started at 250 and ramped up adding 50 a day over a week to 500, in groups of 100. I take it at moderate speed and do a little double jump in between each skip, which really works out my calf muscles. Aside from its general health benefits, cardio exercise releases human growth hormone when sustained for at least 10 minutes, which I believe will help the DNA Appliance do its job.

After exercise I cool off with some cold-water therapy via a dip in the ocean. It’s the first day of spring here and taking winter swims hasn’t always been something that has appealed to me. However, I’m aware proponents like Wim Hof advocate it for health benefits, and the shock of the cold water prompts a release of cortisol which is likely to help my frozen shoulder recover. I was a little reluctant to try this given that exercising in the cold inhibits the release of human growth hormone, but I can’t really swim anyway given my shoulder still has restricted mobility so I rely on the skipping for exercise while relatively warm. I didn’t find any research showing that jumping in cold water after warm exercise negated the growth hormone effect of the exercise. So far after a week of this the results seem promising as my shoulders are a little more mobile and less painful. I’m also getting used to the initial shock of the cold which makes me feel like the Ice Man himself!

I also do 30 bicep curls, lat pull-downs, squats, push-ups and standing rows a day during the week, plus most days about an hour each of singing, drums and keyboard practice.

I get really tired in the evenings and sometimes to go to bed between 8 and 9 PM, especially if I haven’t slept particularly well the night before. I don’t go out at night; but I rarely go out at all given Sydney is in COVID lockdown and all my university lectures are online as a result anyway.

My appliance usage remains excellent at an average of 16.38 hours/day, with the facemask about 3 hours/day this month. I haven’t been sleeping with the facemask but I’m going to start again now my health has improved, and the warmer weather should make it more practical. Wearing it during the day is a pain in the ass and sleeping with it is the obvious way to clock up serious hours using it.

Eleven Months Vivos mRNA Appliance Usage

I realised last month that my meticulous records of screw turns had been compromised because the screws wind themselves backwards over time, so the calculations in my spreadsheet don’t match the actual expansion of the appliance. To counter this, I’ve been diligently checking and correcting the screw positions every morning and will only report actual expansion measurements from the appliance from now on; although the forward adjustment on the upper appliance is difficult to measure due to the Y shape so an estimate for it will have to do.

In total so far, I’ve expanded the lower appliance 5.5 mm sideways, the upper appliance 6 mm sideways and I estimate 5 mm forward.

This month’s CPAP pressure trend analysis is encouraging as it shows a slight downward trend:

Eleventh Month Vivos mRNA Appliance CPAP Pressure Trend

The only bummer is that the median pressure was actually lower to begin with in the first month of my Vivos mRNA Appliance treatment, so this month’s improvement still isn’t quite enough to reverse the overall upwards trend in pressure, but it’s getting there. The blue line indicating the Median Pressure trend is almost horizontal now:

Eleven Months Vivos mRNA Appliance CPAP Pressure Trend

My AHI continues to decline this month due to an ongoing reduction in central events, which could be due to:

This continues the dramatic drop in the overall AHI trend:

Eleven Months Vivos mRNA Appliance AHI and Event Trend

I still wouldn’t say I wake up feeling truly refreshed after a nightly threesome with Vivos and Resmed; they’re not really my ideal choice of bed partners. I still wake up with a mild tension headache every day and remain hopeful that in time I’ll be able to ditch CPAP, then the DNA Appliance, and finally get a really good night’s sleep.


Graham Stoney

I'm a guy in his early 50's, recovering from Chronic Fatigue Syndrome and Severe Obstructive Sleep Apnea.

8 Comments

Sam · September 17, 2021 at 1:16 AM

It seems like it doesn’t work. I’m willing to bet that you still have chronic congestion. You haven’t mentioned anything about how much you can breath now through your nostrils. You should be noticing changes by now. I don’t think vivos dna works. Thanks for recording your treatment for us. Think I’ll look into mse. Kasey li’s ease looks kind of promising but I bet you scar tissue forms around the cut in the maxilla, making your nose just as congested or even more congested than before. I think Mse seems most promising, you just have to make sure it’s expanding evenly on both side so you don’t get one side expanded more. Just my conclusion after looking into all this for over a year. The problem we are all facing is chronic congestion due to narrow maxima. You aren’t mentioning anything of that sort. I appreciate you recording your journey. Thank you Graham.

    Graham Stoney · September 17, 2021 at 7:30 AM

    I don’t think chronic nasal congestion is the cause of my problem. We are not necessarily all facing the same problem. My problem is that my mandible is too far back and my tongue blocks my throat during sleep. I hope you find a solution for your problem. Cheers, Graham

      paco · September 29, 2021 at 9:49 AM

      so you have chronic nasal congestion? i recommend looking into diet for that ie eliminating dairy, wheat.

Kevin · September 2, 2021 at 12:35 PM

Thanks for the updates Graham (and everyone else).
I’m delighted when I hear others making progress.
I’m reasonably sure that people are aware of James Nestor’s book: Breath, The New Science of a Lost Art. If you have not read it or heard Nestor on the Joe Rogan podcast it’s well worth your while. The book proved to be the tipping point for me, to take the plunge with Vivos.

Clark · September 2, 2021 at 11:09 AM

Good to hear your AHIs are gradually decreasing, it seems to be matching the decrease in my compliance hours! I can’t even keep to a 12 hours a day for 10 days, nevermind 16 for 7…

Having actually done more and more myofunctional therapy from July, I have had to wind back the screws on the appliance as my tongue now exerts significant more force onto my maxilla, I have wound back from 11-10 turns transverse down to about 5-6 as I was experiencing tightness and molar gum soreness, I suspect the screws turning themselves back or slipping from its proper fit creates a false sense of progress

Dr Dev Banerjee analysed my sleep study and found ~5 AHI with a median of 92% O2 sat, could be better but defnitely no OSA, what he did find was prominent alpha waves intrusion during sleep, busy brain syndrome / hyperarousal as it is called, and I have now been prescribed with 25mg CBD during day for anxiety and 50mg for sleep

While I dont have generalsed anxiety or PTSD, my current living arrangements have been highly stressful for a number of years, this is actually reflected in my blood pressure despite 20 BMI and no family history or risk factors, I may have inadvertently been in symptom denial this entire time, as well I kept comparing my not-symptoms™ to friends with much more severe GAD/PTSD, which is a terrible benchmark, I am moving in a few months, and I suspect i’d need a laughably high sigma to fish for a p-value for a null hypothesis

While I fear I have jumped into Vivos with way too much enthusiasm in idealising it as a one stop consumerism solution for all my life’s problems (it actually does do that, just not for my symptoms), it will actually widen my very restricted posterior nasopharynx to lessen nasal airflow resistance, when I try to do box breathing, I actually feel like I am slowly suffocating, so while my primary complaint symptoms won’t be resolved by Vivos, I’d still be getting the absurdly long list of benefits some of which contributes to my primary factor symptoms anyway (rapid shallow breathing puts sympathetic/fight or flight back on a hair trigger ? hyperarousal during sleep ? low sleep quality leads to day time stress and anxiety ? cycle repeats)

Emma Cooksey · September 2, 2021 at 12:22 AM

Thanks for the update! Can you remind me which program you use for tracking your AHI trends? Is it OSCAR? I’m the least techy person but I’m on month 3 with DNA and it might be nice to see more data than the myAir app gives me.

    Graham Stoney · September 2, 2021 at 8:07 AM

    You’re welcome; I’m glad you find it helpful. Your recent interviewee Chris Kelly confirmed my theory that Auto CPAP pressure should decline as expansion treatment progresses if it’s really improving the airway. Yes, I use OSCAR to extract the data from my CPAP machine’s CF card, which I then export to a CSV file and import into an Excel spreadsheet to do the trend analysis. Cheers, Graham

      Sam · September 17, 2021 at 1:18 AM

      This tells me that there is no real expansion happening. You haven’t mentioned anything about your congestion improving . Thank you Graham for recording your journey.

Leave a Reply

Avatar placeholder

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.